A study led by scientists from the University of Edinburgh reveals that long-term use of a common painkiller, paracetamol, may have detrimental effects on heart health, particularly for individuals with high blood pressure. Published in the journal Circulation, the research highlights the need for cautious prescribing of paracetamol for chronic pain management. The study aimed to assess the impact of prolonged paracetamol usage on cardiovascular health, specifically in people with hypertension.
In comparison to non-steroidal anti-inflammatory drugs (NSAIDs), which are known to increase blood pressure and the risk of heart disease, paracetamol is often recommended as a safer alternative. However, the research involving 110 patients with a history of high blood pressure found that those taking paracetamol experienced a significant increase in blood pressure compared to the placebo group. The rise in blood pressure observed was comparable to that associated with NSAIDs, potentially elevating the risk of heart disease or stroke by around 20%.
These findings have important implications for both patients and healthcare providers. It emphasizes the necessity of reevaluating long-term paracetamol prescriptions, especially for individuals with high blood pressure or those at risk of cardiovascular diseases. Doctors and patients are advised to carefully consider the risks and benefits of continued paracetamol use, particularly for patients at risk of heart conditions. Opting for the lowest effective dose of paracetamol for the shortest duration is recommended to mitigate potential risks.
The study also prompts a broader reassessment of commonly used pain management drugs and their long-term impacts on cardiovascular health. It highlights the importance of personalized medicine, where treatment plans are tailored to individual patient risks and health profiles.
In conclusion, the study conducted by the University of Edinburgh sheds light on the cardiovascular implications of long-term paracetamol use, especially for individuals with high blood pressure. It calls for a careful review of prescribing practices and advocates for a more nuanced approach to managing chronic pain in patients at risk of heart disease and stroke. The findings emphasize the need for healthcare providers and patients to weigh the potential risks and benefits when considering long-term paracetamol use for pain management.
