Deadly Tick-Borne Virus Claims American Woman’s Life in Balkans, North Macedonia

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A tragic incident in the Balkans has raised concerns for American travelers this summer. An American woman lost her life to a highly infectious and deadly tick-borne virus while on vacation in the region. The public health authority of North Macedonia reported a lethal case of Crimean-Congo haemorrhagic fever (CCHF) on July 30, 2023.

The victim was a 27-year-old agricultural worker who noticed a tick on her abdomen and had it removed on July 19. Just two days later, she developed a fever and was admitted to the infectious department of a hospital in the city of Å tip. Despite receiving treatment, her condition worsened, and she was transferred to the PHI University Clinic for infectious diseases and febrile conditions in the capital city of Skopje. Tragically, the woman passed away on July 27.

Crimean-Congo haemorrhagic fever (CCHF) is a severe disease caused by a virus transmitted through tick bites. It can trigger outbreaks of viral haemorrhagic fever, posing a significant public health threat due to its high fatality rate of 10-40%. The virus is prevalent in regions such as Africa, the Balkans, the Middle East, and parts of Asia below the 50th parallel north, where ticks are the primary carriers.

The illness affects various animals, including livestock such as cattle, sheep, and goats. In some cases, birds like ostriches can also become infected, potentially contributing to human cases. Animals contract the virus through tick bites, which allows the virus to circulate in their bloodstream. The primary tick species responsible for transmission is the Hyalomma genus.

Humans can contract CCHF through tick bites or by coming into contact with infected animal blood or tissues, particularly during and after slaughter. It primarily affects individuals working closely with livestock, such as agricultural workers, slaughterhouse employees, and veterinarians. Inadequate sterilization and contamination of medical equipment in hospitals can also lead to human-to-human transmission.

Symptoms of CCHF can vary depending on how the virus is acquired. Tick bites typically result in an incubation period of one to three days, while contact with infected blood or tissues can take five to six days. The initial symptoms include fever, muscle aches, dizziness, neck pain, headache, sore eyes, and light sensitivity. Nausea, vomiting, diarrhea, sore throat, and abdominal pain may also occur. In severe cases, the virus can cause bleeding rashes on mucosal surfaces, enlarged lymph nodes, and liver damage.

Diagnosing CCHF virus infection involves various laboratory tests, including ELISA, antigen detection, serum neutralization, RT-PCR assay, and virus isolation. However, handling patient samples for testing is hazardous and requires strict containment.

Although there is no specific treatment for CCHF, supportive care to manage symptoms is crucial. The antiviral drug ribavirin has shown potential benefits in treating CCHF infection. Additionally, preventive measures such as tick avoidance and proper hygiene when handling animals or animal products can help reduce the risk of infection.

As news of this tragic incident spreads, American travelers are urged to take precautions while traveling to regions where CCHF is prevalent. It is essential to use insect repellent, wear protective clothing, and perform regular tick checks. If any symptoms develop after potential exposure to ticks or infected animals, seek medical attention immediately.

The loss of this American woman’s life serves as a stark reminder of the dangers posed by tick-borne diseases. It is crucial for individuals traveling to high-risk areas to be aware of the risks and take appropriate measures to protect themselves. By staying informed and practicing preventive measures, future cases of tick-borne illnesses can be minimized, ensuring safer journeys for all travelers.

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Rohan Desai
Rohan Desai
Rohan Desai is a health-conscious author at The Reportify who keeps you informed about important topics related to health and wellness. With a focus on promoting well-being, Rohan shares valuable insights, tips, and news in the Health category. He can be reached at rohan@thereportify.com for any inquiries or further information.

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